Clinical Repository to Understand, Study, and Heal Myelodysplastic Syndrome |
Overview of Clinical Trials: Clinical Trials 101 video
Title: Predicting Response to Your Myelodysplastic Syndrome (MDS) Treatment
Title: CMML: A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib for the treatment of Chronic Myelomonocytic Leukemia (CMML) and Cataloging the Molecular Consequences of JAK2 Inhibition in Chronic Myelomonocytic Leukemia (CMML): A Correlative Study Identifying Targetable CMML Sub-Clones by Leveraging GM-CSF Dependent pSTAT Hypersensitivity
Sponsor: Moffitt Cancer Center
Principal Investigator: Rami Komrokji, M.D.
Title: Phase II Randomized Study of Lower Doses of Decitabine (DAC; 20 mg/m2 IV daily for 3 days every month) versus Azacitidine (AZA; 75 mg/m2 SC/IV daily for 3 days every month) versus Azacitidine (AZA; 75 mg/m2 SC/IV daily for 5 days every month) in MDS Patients with Low and Intermediate-1 Risk Disease Transfusion-Dependent versus Best Supportive Care (BSC) in MDS Patients with Low and Intermediate-1 Risk Disease Transfusion-Independent (Study 2014-0112)
Sponsor: MD Anderson Cancer Center
Principal Investigator: Guillermo Garcia-Manero, M.D.
Title: Interventional Validation of an MDS-Specific Measure of Quality of Life: Assessing the Responsiveness of the QUALMS-1 to Different Hypomethylating Agent Regimens for Low and Intermediate Risk Disease (Companion protocol to MD Anderson Cancer Center Study 2014-0112)
Sponsor: Dana Farber Cancer Center/Cleveland Clinic Foundation
Principal Investigator: Gregory Abel, M.D., MPH / David Steensma, M.D.
Title: Characterization of Mutation Profiles and Outcomes in MDS and AML
Title: A Phase 2 Study of SGI-110 in Philadelphia-Negative Myeloproliferative Neoplasms
Sponsor: Weill Cornell Medicine
Principal Investigator: Dr. Gail Roboz
